The 2 big issues are (1) Is molecules to man evolution well supported by good science or not, and (2) is it consistent with the Christian religion, the '...faith that was once for all revealed to the saints' (letter of Jude verse 3). They are clearly connected but need in my view to be considered each on its own merits. I share the view of fellow Christians who accept evolution that if science and religion appear to be in conflict, then either the science or religion are wrong (so one or the other should be reviewed and perhaps rejected at the point of disagreement,) or we have misunderstood one or the other and the apparent disagreement is illusory if we can only see it. A lot of misunderstanding creeps in at this point, with Christians who reject evolution theory typically being accused of failing to understand either it or the principles of science. But for today, I want to look at some of the biology.
'Without the variations, natural selection would have nothing to work on'. (Charles Darwin, 'Origin of Species'
Or (C) do they falsify evolution's central mechanism by demonstrating that random mutations in fact destroy meaningful DNA information rather than create it?
We've also found a mutation in a membrane receptor protein that confers resistance to HIV. It's thought to be a remnant from resistance to the bubonic plague or smallpox, and that it prevents HIV from binding to cells. Like the wisdom teeth, there hasn't been recent selective pressure for it to spread throughout the population, though this time because HIV hasn't been around for very long (really only one or two generations), and hasn't been widespread enough for strong selective pressure.
Why limit yourself to animals, though? We're fundamentally the same as single-celled organisms when it comes to mutations and evolution. The Lenski lab recently observed the generation of a new mutation that allowed a population of E. coli to metabolize citrate, which they were unable to use as an energy source before. ‘
andymanec unequivocally stated that sickle cell is a beneficial mutation. Of course, there is no dispute that it confers some survival benefits in the face of falciparum malaria, a microbial parasite spread by biting mosquitos which can kill a previously healthy person in 48 hours and is still one of the biggest killer diseases worldwide. But how does the mutation confer benefit? By making screwed up haemoglobin which in turn leads to deformed red blood cells which are so dysfunctional that the malaria parasite can’t survive so well in them.